How is MSG made?
MSG (monosodium glutamate) is a common food additive that is widely used to enhance the umami taste of food. Its production process involves microbial fermentation and chemical extraction. The following is the detailed production process and related data.
1. History and uses of MSG

MSG was first extracted and discovered from kelp by Japanese scientist Ikeda Kikunae in 1908, and was later promoted to the world through industrial production. Today, MSG has become an indispensable condiment in the kitchen and food industry, especially in Asian countries.
2. Raw materials for making MSG
The main raw material of MSG is starch or molasses, which is produced through microbial fermentation to produce glutamic acid, which is then made through steps such as neutralization and crystallization. The following are the main raw materials and their functions:
| raw materials | function |
|---|---|
| Starch (corn, wheat, etc.) | Provides carbohydrates needed for fermentation |
| Molasses (sugar cane or beet) | Replace starch as fermentation substrate |
| Microorganisms (Corynebacterium glutamicum) | Convert sugars to glutamate |
| Hydrochloric acid or sodium hydroxide | Adjust pH value and promote crystallization |
3. Production process of MSG
The production of MSG is mainly divided into the following steps:
| steps | Specific operations |
|---|---|
| 1. Raw material handling | Hydrolyze starch or molasses into glucose as fermentation substrate |
| 2. Fermentation | Add Corynebacterium glutamicum and ferment at 30-37°C for 24-48 hours |
| 3. Extract glutamic acid | Isolation of glutamic acid from fermentation broth by centrifugation or filtration |
| 4. Neutralize crystallization | Neutralize glutamic acid with sodium hydroxide to form sodium glutamate solution, which is then recrystallized and dried. |
| 5. Finished product packaging | The crystallized MSG is crushed, screened, and packaged into products. |
4. Nutrition and safety of MSG
The main component of MSG is sodium glutamate, which has low calories and contains about 12 kcal per 100 grams. Regarding its safety, the International Committee on Food Additives (JECFA) and the US FDA have recognized MSG as a safe food additive, but it is recommended to use it in moderation.
| Ingredients | Content (per 100g) |
|---|---|
| monosodium glutamate | ≥99% |
| Moisture | ≤0.5% |
| Chloride | ≤0.1% |
5. Substitutes for MSG
With the popularity of healthy eating, some consumers choose natural flavoring agents to replace MSG. Common alternatives include:
| Substitute | Features |
|---|---|
| yeast extract | Rich in natural glutamic acid, no chemical additions |
| kelp powder | Contains natural umami ingredients, but costs more |
| Mushroom essence | Extracted from shiitake mushrooms, unique flavor |
6. Summary
MSG is a food additive made by microbial fermentation of starch or molasses. Its production process is mature and its safety is widely recognized. Despite the existence of natural alternatives, MSG remains an important ingredient in the food industry due to its low cost and effectiveness. Reasonable use of MSG can add delicious flavor to dishes without affecting health.
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